Multiple Sclerosis Breakthroughs - News and Research
Rights and Responsibilities of MS Clinical Trial Participants
Clinical trials are essential for getting new treatments to market. It is important that people who participate in clinical trials understand their rights and responsibilities as trial participants, so that the process can function smoothly.
How to Read a Scientific Article About MS
Reading articles in medical journals can seem like a daunting task. Learn how to approach these articles strategically to get the most out of them.
Questions to Ask Before You Sign Up for an MS Clinical Trial
Participating in a clinical trial for multiple sclerosis (MS) can be an exciting process. However, you need to understand what is expected from you as a participant. Use the following list of questions to help you think about what you want to know before signing on to participate in a clinical trial.
Q. What Does It Mean When a Research Result is "Statistically Significant"?
The term "statistical significance" basically means that a result was unlikely to happen by chance. It is a scientific way of comparing the results of a research trial or study.
What Causes CCSVI?
CCSVI, or chronic cerebrospinal venous insufficiency, is the narrowing of the veins leading from the brain and spine and is being investigated as a possible cause of multiple sclerosis (MS). There are thoughts that CCSVI is a congenital disorder or the reaction to an infection.
What Is CCSVI in Multiple Sclerosis?
CCSVI stands for chronic cerebrospinal venous insufficiency, which means that the veins leading from the brain are not draining blood as efficiently as they should. Research shows that people with multiple sclerosis (MS) are very likely to have CCSVI and it may be a cause of MS.
Clinical Trials and People with Multiple Sclerosis - Clinical Trial E…
Clinical trial participation is often very exciting, but also comes with new responsibilities. Share your story and learn from others who have participated in clinical trials for people with multiple sclerosis.
Does Mono (Epstein-Barr Virus) Cause Multiple Sclerosis?
The Epstein-Barr virus has long been a suspect as a possible cause of multiple sclerosis. Many people with multiple sclerosis also have a history of a case of mono (mononucleosis or "glandular fever"). Could the Epstein-Barr virus be the key to understanding the cause of multiple sclerosis?
How Smoking Makes Multiple Sclerosis Worse
Smoking cigarettes is associated with a higher risk for multiple sclerosis (MS) and increased progression of the disease. Many theories have been proposed as to why smoking worsens risk and progression of multiple sclerosis.
Aspirin as Treatment for Fatigue in Multiple Sclerosis
A study showed that aspirin at high doses may provide relief from the fatigue associated with multiple sclerosis (MS).
Tovaxin is a vaccine for multiple sclerosis (MS) that uses a person's own T-cells. Tovaxin is made by Opexa Therapeutics. It is still in the clinical trial stage, but so far results have been excellent. Learn more about Tovaxin.
How is Tovaxin Made?
Tovaxin is a multiple sclerosis (MS) vaccine that is made from an individual's own T-cells. Learn how Tovaxin is made.
MS vaccines are currently being tested in clinical trials. These are different from vaccines that we normally think of: they are therapeutic, rather than preventive and they are not protecting us against infectious diseases, but our own immune systems. Learn more about MS vaccines.
Intestinal Parasites Protect Against Multiple Sclerosis Relapses
A study in Argentina demonstrated that people with multiple sclerosis (MS) who were infected with intestinal parasites had far fewer relapses than uninfected people. Clinical trials using parasite eggs to reduce MS relapses are currently underway.
Why Are There So Few Clinical Trials for People with PPMS?
Clinical trials for primary progressive multiple sclerosis (PPMS) present a number of huge challenges that limit the amount of research done into treatment for this form of MS.
A pilot study is a smaller version of a larger study that is conducted to prepare for that study. They are sometimes known as feasibility studies, if the objective is to determine the likelihood of success of a larger study.
Patients participate in each arm of the study in random order. They are not appropriate for testing the disease-modifying therapies for multiple sclerosis (MS), but may be used to test drugs and procedures targeting MS symptoms.
Doctors Not Prescribing Enough MS Drugs
A study shows that a shocking majority of people with multiple sclerosis (MS) are not taking one of the disease-modifying therapies. Learn more about the details of this study, “Analysis of NAMCS data for multiple sclerosis, 1998-2004.”
NeuroVax is a therapeutic vaccine for multiple sclerosis (MS). In March 2007, Orchestra Therapeutics (formerly the Immune Response Corporation) launched a large Phase II trial in Europe to test safety and efficacy.
How Can I Find an MS Clinical Trial?
Finding an MS clinical trial is easy. All US clinical trials are listed in a database kept by the government. With a simple search, you can discover if an MS clinical trial fits your needs.
Who Can Join a Clinical Trial?
Each clinical trial needs certain types of participants. These conditions vary based on the drug being tested and may include: type of MS, severity of MS, time since diagnosis, previous treatment history and other conditions.
Understanding MS Clinical Trials
Clinical trials test new treatments and medications. It can take many years before a new treatment is released to the public. For the latest in research and the opportunities to access a new treatment, you need to understand clinical trials, how to evaluate them and how to find a clinical trial.