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Basal Ganglia

By Julie Stachowiak, Ph.D., About.com

Updated: May 21, 2007

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Definition: The basal ganglia refers to large clusters of nerve cells which are located within the cerebrum and upper parts of the brain stem. These structures help start and stop movement, as well as keep movements smooth and fluid.

Multiple sclerosis can cause damage to the basal ganglia, which can produce a variety of symptoms, including: tremor, involuntary movements, weakness and spasticity.

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