A T1-weighted magnetic resonance imaging (MRI) scan shows “black holes,” which are areas of permanent axonal damage. These are called hypointense lesions, meaning that they display as dark areas on the MRI image. T1-weighted lesions can also be areas of edema (swelling), which are not permanent and disappear on subsequent scans.
The T1-weighted scan is part of conventional MRI technology which is used to monitor and diagnose multiple sclerosis (MS), usually in conjunction with a T2-weighted scan and with gadolinium enhancement.

